Skin Cancer Reconstruction (Pourtaheri 4/13/2022)

Many thanks to Dr.  Navid Pourtaheri, new-to-our-community plastic surgeon, on Skin Cancer and Skin Cancer Reconstruction. This is a great summary of skin cancer findings and some specific indications and recommendations of when to involve plastic surgery. 

A recording is available HERE 

Skin cancer types: basal cell (BCC) squamous cell (SCC) keratoacanthoma, melanoma

Basal cell cancer (~4 million cases/year in US)

  • variable in appearance, "can look like anything"-- don't know what it is until you remove it
  • always slow growing (even high risk ones)
  • primarily occur on sun-exposed areas (hand, ears, face)
  • do sometimes spontaneous bleed or ulcerate
  • can be locally invasive
  • very rarely metastasize
Squamous cell cancer (SCC), 1.5 million cases/year in US
  • variable appearance, but more commonly dry and scaly, also can be rough/thickened, wart-like, can ulcerate and form open sores
  • more accelerated growth with local invasion than BCC (tend to progress more quickly)
  • lower lips more common with SCC 
  • can be locally invasive, can metastasize
  • curable if treated early
  • actinic keratoses (AK) is pre-squamous cell lesion
Keratoacanthoma, 275K cases/year in US
  • once considered subset of SCC
  • dome-shaped lesion with central keratin plug
  • almost always in sun exposed areas (face, ears, nose, hands)
  • quite rapidly growing (faster than SCC), can be locally destructive
  • unpredictable, can spontaneously regress
  • less likely to metastasize
Melanoma, 197K cases/year in US
  • most costly type of skin cancer
  • 25% found in existing moles, 75% spontaneously occur on normal looking skin
  • 50% are melanoma in situ>> high cure rate (90-100%)
  • can be found ANYWHERE
  • most common form is superficial spreading
  • when goes deeper, called lentigo maligna
  • 10-15% of cases are nodular melanoma, most aggressive, tends to be found invading
  • remember ABCDE (see below) with special attention to "E" (evolving-- that is a changing mole)
  • Breslow thickness correlates with 5-year survival


Treatment options for skin cancer
  • Moh's surgery 
    • most commonly used in BCC and SCC (often contraindicated for melanoma)
    • high risk areas (H zone)
    • cosmetically sensitive areas, over joint surfaces
    • decreases amount of tissue excised, maintaining the same cure rate
  • Excision with margins and simple closure also acceptable
  • Curettage (EDC)
    • scrape the abnormal tissue, then burn it
  • Cryotherapy more common in older patients, people who don't want a procedure, on blood thinners, large number (e.g. on face)
  • Melanoma best excised w/margins, possible lymph node biopsy (plastic surgery, general surgery)
    • sentinel node biopsy not indicated for melanoma in situ
When to refer to plastic surgeon?
  • skin cancer not indicated for Mohs
  • post dermatology resection, cannot close
  • melanoma
Biopsy options
  • shave: get full epidermis but only part of dermis (this is good because it won't form scar)
    • always inappropriate for c/f melanoma because need full thickness
  • punch: takes full thickness of skin
  • incisional biopsy: get piece of abnormal with normal adjacent, done with scalpel
  • excision: preferred for lesion is <1cm (cut the whole thing out with margin, 1mm of normal tissue is acceptable margin 
  • FNA not used for skin, but for clinically positive nodes
  • Sentinel lymph node biopsy (SLNB) after melanoma diagnosis, after lymphoscintigraphy (radioactive dye that drains to the lymph node)
Imaging
  • Always needed in >Stage 3 melanoma, definitely NOT indicated in stage 1 (stage 2, use your judgement, may be indicated)
  • Most common: PET CT for assessing for metastases
  • Chest CT also good modality b/c melanoma so often goes to lungs (chest xray not sufficient)

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