A recording of the presentation can be found HERE.
Sponsored by the Santa Rosa Family Medicine Residency and Sutter Medical Group of the Redwoods
Diabetes Medications for Cardiovascular, Heart Failure, and Renal Risk Reduction (Magnotti - 7/20/22)
Marijuana Use in Pregnancy and Post Partum (Pinto 6/7/2022)
Many thanks for an excellent Grand Rounds year-- we covered a wide range of topics from Drowning Prevention to Moral Distress, from CKD to Gender Expansive Care, from Racism in Medicine to Bias in Documentation, from Breast Cancer Reconstruction to Alcohol Withdrawal. And more!
Also thanks to our last Grand Rounds speaker of the year, Dr. Vanessa Pinto, who gave an excellent talk on Marijuana (MJ) in pregnancy and postpartum.
A recording of her presentation is available HERE.
My notes:
- In 15-44 year old pregnant patients, 4.9% reported MJ use in the last month during pregnancy (compared to 11% when not pregnant)
- Use during pregnancy has increased since 2015, with significant increases during pandemic
- 44.6% of patients who reported smoking MJ before the pregnancy continued use during pregnancy
- Risks of MJ use during pregnancy include low birth weight, preterm birth (when combined with tobacco), still birth, and long term neurodevelopmental issues
- There are some women that believe that MJ is helpful for hyperemesis and nausea/vomiting of pregnancy. However, there is no data to support this. And we know MJ use is associated with cyclic vomiting syndrome.
- The only state with legislation to caution use of MJ in pregnancy in Oregon
Abnormal Liver Function in Obstetrical Patients (Ludwig, 6/1/2022)
Many thanks to Dr. Alec Ludwig for an excellent presentation about liver and biliary abnormalities in pregnancy. It was jam-packed with good information.
A recording of his presentation is available HERE.
My notes:
Remember that what we typically call "liver function tests" is actually a misnomer. In fact, there is no test that reliably demonstrates the liver's function. Elevation of AST and ALT -- the liver enzymes-- indicates liver injury, not liver dysfunction. Albumin and prothrombin time are factors that are produced by the liver and may be better markers of function.
In normal pregnancy, you can see elevated alkaline phosphatase (up to 3x normal), as well as elevated cholesterol, triglycerides, and fasting gallbladder volume. Note that many measures we use to evaluate the liver (AST/ALT, T Bili, PTT, liver size, bile acids) don't change in pregnancy.
Hepatocellular injury as measured by elevation in AST/ALT:
- acute viral/toxic hepatitis: AST/ALT 25x upper limit of normal
- ischemic hepatitis: AST/ALT 50x upper limit of normal
- chronic HCV/HBV: slight elevation of AST/ALT (2x normal), rarely greater than 10x normal
Gallstone disease in pregnancy
Gallstone disease is much more prevalent in pregnancy for several reasons. 1) Increased estrogen levels increase cholesterol, thereby supersaturating bile with cholesterol. 2) Progesterone slows contraction of gallbladder, disrupting the excretion of bile acids. AND 3) Increased fasting gallbladder volume.
- acute cholecystitis: blockage of the cystic duct causing inflammation in the gallbladder
- fever, WBC count, can have slightly elevated AST/ALT (if large stone)
- choledocholithiasis: stone in CBD or hepatic duct, causing backup into liver, injury to liver
- definite elevation AST/ALT
- acute cholangitis: can be emergency due to severity of illness
- Charcot's triad (RUQ pain, jaundice, fever)
Generally treat GB disease in pregnancy with IV antibiotics, surgery if indicated. Laparoscopic cholecystectomy is safe in pregnancy, safest in the second trimester. Should occur within 24-48 hours conservative management. ERCP is also safe in pregnancy; minimize radiation by shielding, fetal monitoring.
Viral Hepatitis (A-E)
- HAV: most common acute hepatitis in general population, but infrequent in pregnancy.
- Acute infection (only care about IgM).
- Generally mild (malaise, HA, fever, jaundice, RUQ pain), supportive treatment.
- HAV vertical transmission rare but has been documented. Associated with preterm birth, neonatal cholestasis.
- Breastfeeding okay, HAV vaccine safe in breastfeeding
- HBC: surface Ag used to screen everyone in pregnancy, core Ag, e Ag indicated infectivity/vertical transmission to 80-90% if occurring in the 3rd trimester.
- Major causes IVDU, sexual intercourse with people w/HBV, vertical transmission.
- can present with asymptomatic acute phase, can pick up infection even prior to symptoms
- if mom has chronic HBV in pregnancy: need to check viral load, 1 million to 100 million is elevated, may need treatment during pregnancy w/Tenofovir after 28-32 weeks (to prevent vertical transmission)
- Babies born to mothers with HBV needs HB IVIG and first dose of vaccine within 12 hours, don't determine delivery method
- Breastfeeding is safe as long as infant got IVIG and HBV vaccine
- HCV: can be acute and chronic
- HCV on the rise in the last few years (2009-2019 2x increase of patients with HCV), likely due to IVDU
- vertical transmission 3-5%
- 75% HCV infections are asymptomatic
- ACOG does have some recommendations of Category B meds that could be used to treat HCV in pregnancy to decrease vertical transmission (Ribavirin is teratogenic)
- Vertical transmission increases if co-infection w/HIV, invasive surgical procedure, ROM >6 hours, conflicting data but discourage fetal scalp electrode
- Breastfeeding okay w/HCV
- HDV: coexists with HBV only, anyone with chronic HBV should be tested for HDV. Supportive treatment, monitor symptoms. If treat HBV, clears HDV.
- HEV: can be acute and chronic, based on genotype
- some areas in Mexico, Asia, Africa and South America endemic (travel recommendations not to travel to endemic areas in 2nd and 3rd trimester)
- believed to be water born
- pregnancy women are particularly susceptible to severe liver damage and liver failure, 20-30% mortality
- rare vertical transmission
- breastfeeding okay
- Elevated ALT 30x normal, elevated conjugated bilirubin
- generally not jaundiced
- start antenatal testing right away
- treatments (all grade C): ursodiol improved labs and symptoms but no data that improves still birth. Other treatments: Hydroxyzine, cholestyramine
- Some data on PO vitamin K (evolving evidence)
- Can progress: 2-5x risk of progression to preE, if bile acids >40
- BP >160/110 (2x, 4 hours apart) OR
- thrombocytopenia, elevated SCr or liver test abnormalities (regardless of BP)
- Antenatal testing daily, deliver at 34 weeks
Pandemic Pearls and Pivots: A Public Health Perspective (Drs. Mase & Shende, 5/25/2022)
Many thanks to our SoCo Public Health Officer, Dr. Sundari Mase and our SoCo Vaccine Chief, Dr. Urmila Shende for an excellent Grand Rounds this week on Pandemic Pearls and Pivots: A Public Health Perspective.
A recording of their presentation is available HERE.
As we all know, COVID-19 has taken a great toll on our world, our nation, and our county. As of this week, there have been 6.28 million deaths worldwide (probably an underestimate), >1 million US deaths (more have died from COVID-19 than HIV/AIDS, the 1918 influenza pandemic), 90,000 deaths in California, and 491 deaths in Sonoma County. This has led to the largest drop in life expectancy since WWII. And we know that there have been disproportionate numbers of cases, hospitalizations, and death among people of color.
- Building Public Health testing capacity
- SoCo regional lab has done 206,000 (of 1.6 million PCRs total) to date in SoCo
- State of California and FQHC partnerships
- Focus on equity
- bilingual messaging
- pop up testing sites (using local data to determine neighborhoods for sites)
- bilingual/bicultural testing/contact tracing
- With increase in Ag testing (no longer have a denominator), we are beginning to pivot toward wastewater surveillance
- Communication campaigns, outreach, press conferences
- re. masking, hygiene, social distancing, gathering size limitations
- reaching so many different sectors, subgroups was VERY challenging (e.g. reaching the elderly: age, transportation, low tech)
- local radio, social media: FB, instagram, etc, flyers
- work with community based organizations, promotoras essential
- Shelter in place (averted huge surge/disaster early on)
- Alternate care site/non-congregate site (for people with unstable housing, served thousands of people, SSU>>hotels)
- State, local and Bay Area health orders to protect vulnerable populations
- Vaccines
- Magnification of underlying/pre-existing disparities
- Latinx residents: largely essential workers, hardest hit
- 27% of our population is Latinx, accounted 45% of all cases
- at one point, case rate was 9X higher for Latinx
- In 2020, life expectancy decreased by 2.1 years in Latinx population (compared to 0.7 years in White SoCo population)
- Addressing these inequities, THE PUBLIC HEALTH CHALLENGE of this pandemic
- Health Equity Working Group helped get services to vulnerable population
- trusted messengers (community health workers, promotoras)
- vaccines, masks/PPE, rental assistance
- CURA: important partner to reach community, ensuring financial assistance provided to people who needed it ($8 million)
- FQHC network for collaboration--> 13 different vaccine sites to prioritized populations
- Special shoutout to Dr. Jenny Fish and Dr. Panna Lossy for uplifting the voices of vulnerable communities
- 75% of SoCo deaths were in people >65
- residents of skilled nursing facilities were particularly vulnerable prior to the introduction of vaccines
- SoCo PH chose to prioritize the most vulnerable residents for vaccine roll out
- older adults (65+, 75+)
- SNF and residential care facility patients (RCF)
- Essential workers and marginalized communities (health workers, farm workers, food service workers, homeless)
- We have very high degree of vaccination in our elders: 93% of those >65 are fully vaccinated
- Vaccination of vulnerable elders reduced deaths at SNFs and RCFs
Vaccines work! The reduce infection, hospitalization, and deaths.
| from https://socoemergency.org/ |
Be Curious (Jordan, 5/18/2022)
If you are interested in this week's Grand Presentations Be Curious: Cultivating Curiosity in Learners, Teachers, and Practitioners of Family Medicine, a recording is available HERE.
I will be brief with my notes:
I presented Dr. Todd Kashdan's model for the 5 Dimensions of Curiosity:
- Joyful exploration: pleasurable, knowing for the simple sake of knowing
- Deprivation sensitivity: the itch you must scratch, can be uncomfortable, even painful
- Social curiosity: interest in knowing what makes people tick
- Stress tolerance: discomfort with novelty, mystery, unknown
- Risk tolerance/thrill seeking: desire for thrill, adventure
“Curiosity is fundamental to our physicianship, and serves both the art and the science of medicine. (How do you do? What’s your name? Where do you come from? How do you feel? Tell me more about this pain you’re having…). Curiosity is how we explore the world, this primal “wonderment” that stimulates exploration, engages both the human imagination and human intelligence. Both are integral to the humanities and science, as well as the synthesis of the two, which is clinical medicine.”https://www.bumc.bu.edu/facdev-medicine/files/2010/09/Fitzgerald_AnnInternMed_1999_130_70_Curiosity.pdf
I also shared with you a model created by an Israeli hematologist, Dr. Shattner, in his essay from 2015 on Curiosity in medicine. His model (which I don't love aesthetically but adore in its core tenets) espouses that curiosity is good cognitively and emotionally, and it's good for patients and physicians.
You can see his model below and an updated rendition below (by yours truly)
Shattner, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484215/ |
- What happens if you are truly curious about a patient’s chronic pain?
- Or their itchy scalp?
- Or their dietary habits?
- What happens if you are curious about a surgeon’s outburst?
- Or an administrator’s edict?
- What happens if you are curious about your own wrist pain?
- Or why it is that physicians don’t take lunches?
Cardiology Potpourri (Tsai, 5/11/2022)
Thanks to our speaker this week, cardiologist Dr. Joanne Tsai, for an excellent review of cardiology topics for outpatient care of cardiology patients, particularly regarding Atrial Fibrillation and Atrial Flutter.
A recording of her presentation is available HERE.
My notes:
- When in doubt, get a 12 lead EKG
- That being said, accuracy of EKG interpretation is shockingly poor:
- 42% for med students, 55% residents, 69% primary care, 75% cardiologists
- It is super important to provide clinical framework for the EKG reader; clinical information definitely increases accuracy
- The most common errors with computerized EKG interpretation occur with sinus arrhythmia (computer only accurate 55% of the time) and AV nodal conduction disturbances (2nd, 3rd degree AV block)
| pseudo atrial flutter |
- "C"=in the CHA2DS2 stands for CHF; however, guidelines are quite vague in the case of HFpEF and whether CHF should be considered if pt history vs. symptomatic
- Of note, people with OSA have higher risk of stroke (compared to people without OSA), so assessment for OSA is of utmost importance
- Lifetime prevalence of developing AFib for a 40 year old in the US is 1 in 4 (compared to breast cancer 1 in 8)
- overlap between Afib and OSA is 80-90%
- it's really important to get patients with HFpEF into sinus rhythm (and out of AFib)
- even though the AFFIRM trial found that rate control> rhythm control, Dr. Tsai argued that most of these trials excluded people with HFpEF
- that for patients with AF and HFpEF, we really need to put them into sinus rhythm, including anti-arrhythmics
- weight loss is associated with decreased CV mortality in A Fib
- TTE (looking for ejection fraction, evidence of genetic disorder e.g. hypertrophic cardiomyopathy), EKG (looking for prior infarct, LVH, evidence of genetic disorder), sleep study (looking for OSA), ischemia evaluation
- Don't forget exogenous toxins (e.g. alcohol-- direct cardiogenic effect at the level of the atria)
- hypertrophic cardiomyopathy
- hyperthyroid (especially when actively thyrotoxic; once no longer some will stop anti-coagulation; others continue because still hypercoagulable)
- moderate-severe mitral stenosis
- mechanical heart valves
- getting a good history regarding the loss of consciousness can determine cause 90% of the time without any testing
- face to face conversation, ask open ended questions
- "How many times have you passed out/lost consciousness?"
- Calculators for syncope evaluation:
- San Francisco Syncope Rule
- Dr. Tsai prefers the EGSYS (Evaluation of Guidelines for Syncope Study)
Let's Talk about Sex (MacArthur 5/4/2022)
Big thanks to Dr. Sophie MacArthur for her excellent presentation on a topic that we could ALL use a little education on-- Sex. And specifically how we talk about it with patients.
The recorded presentation is available HERE.
Link to her slides is HERE.
My notes:
- The Sex Ed most of us had in school wasn't any good
- a meta-analysis of 48 different studies in 10 countries (including US) in BMJ found high school students believed their sex ed to be impractical, out of touch, sexist, heteronormative, and embarrassing
- And. .. let's face it. Physicians aren't very good at talking about sex with patients.
- While 88% of primary care physicians say they take a sexual history, only 25% of charts have said history recorded
- A study from the 1990s-- height of the AIDS epidemic-- found providers didn't take sexual history because they didn't feel it was relevant, didn't feel well-trained, and felt embarassed
- We are inadequately trained
- We tend to discuss sex only when patients ask
- But. . .patients want to talk about sex!
- In one large study from Europe, 91% of patients want their physicians to ask about their sexual history and sexual health
- Even of the 15% who would feel embarrassed talking about sex, 75% still wanted their doctor to ask
- it is not heteronormative
- it allows us to screen people for STIs at appropriate sites (e.g. for rectal, oral GC/CT)
- Permission ("May ask you a few questions about your sexual health and sexual practices?")
- Partners ("Do you have any new partners in the last 12 months? How many? Do your partners have any risk factors?"
- Practices ("When you have sex, what parts of your body come in contact with what parts of someone else? And how?")
- Protection from STIs ("Do you and your partners discuss protection from STIs? "What methods do you use? How often do you use them?")
- Past history STIs ("Have you ever been tested for STIs? Have you ever had an STI?")
- Pregnancy intention ("Do you think you would like to have (more) children some day?")
- Ask routinely, confidentially and free of assumptions
- Do it often (you will get better at it)
- Explain why it's important to know what you are asking
- Ask about function and satisfaction (not just about STI risk)
- Use open ended questions (e.g. "what types of sex do you have?"), at least initially
- Normalize less desired responses (e.g. many people don't consistently use condoms; how often do you find yourself not using a condom?")
- Mirror patient's language if possible
- Make the interaction as natural as possible (not robotic)
- Give patients the option to answer questions indirectly (e.g. I recommend screening for GC/CT in all the sites that may have been exposed; for example, the throat, the anus, the penis, the vagina. Which of these sites should you have tested today?)
- Tone and rapport matter, at least as much as the questions
STIs: Not just condoms - frequent testing, PrEP or PEP, etc.
Contraceptives: RHAP Birth Control Options Fact Sheet; bedsider.org
Consent: Yes, No, Maybe Inventories
Painful sex: Mayo Clinic resources
BDSM/Kink safety: San Francisco Aids Foundation S&M and Kinky Sex Resources; NCSF Kink Aware Professionals Directory
Legal: National Coalition for Sexual Freedom Incident Report; safewordtax.com
Strategies to Build Resilience and Happiness: The Art and Science of Gratitude (Lo, 4/27/2022)
I am personally feeling very grateful to Dr. Onna Lo for a really lovely presentation this week on Gratitude, Happiness and Resilience. I have already integrated some of her techniques. . .priming my day and granting myself a "celebration" list (what I have accomplished in the last 24 hours) rather than a "todo list" (all the things I feel bad about not accomplishing).
If you are interested in watching her presentation-- and you should be -- it is available HERE .
Here are my notes. sorry they are brief:
Dr. Lo encouraged us to start every day and every encounter with the ABCs:
A: Awareness (ground yourself)
B: Body/breath (be in your body, find your breath)
C: Connection (with your surroundings, yourself, your patients)
People are struggling
- 36% of Americans are cognitively tired
- 44% of Americans are physically tired
- Depression rates have increased over the last decade from 8% to 22% to 32% in 2022
Something to strive for -- Dr. Lo recommends in our own lives and for patients. To be: Empowered, Engaged, Excited, and Embodied
Some definitions:
- Reactive gratitude: appreciation for a gift received
- Active gratitude: seeking out gifts occurring in life that are appreciated
- Happiness: enjoyment of the present good
- Hope: desire for valued future
- Resilience: the ability to prepare for, recover from, adapt in the face of adversity, stress or challenge
Lesson #1: A positive mindset sets you up for better learning
A positive mindset leads to better learning, improved performance, better problem solving
In The Happiness Advantage, author and researcher Shawn Achor, proposes that personal happiness leads to professional success (not vice versa). Happiness is a choice. Happiness spreads. Happiness is an advantage. Read more about his work here.
The happier you are, the more successful you will be (Horn & Arbuckle).
Gratitude predicts hope and happiness more than forgiveness and patience.
How can YOU build happiness? 21 days in a row x 2 minutes >> 3 gratitudes, positive journaling
Lesson #2: Our brains tend to get stuck in negativity
Half glass full or half empty?
Dr. Lo showed us a series of sociological experiment in which people consistently chose the negative response consistently after being primed with a negative response, even when the outcome was quite positive. If primed with the positive response, people were more likely to choose positive.
We can unstick ourselves by "priming"-- that is, retraining the mind first thing in the morning with gratitude. That is, starting the day positive allows for the day to be more positive.
Exercise: Draw a triangle, write down 3 gratitudes (these must be heartfelt!)
2) what I am grateful for in others
3) what I am grateful for in my current situation
Exercise: Draw a triangle, write down 3 wonderful things that you accomplished in the last 24 hours (this is your celebration list)
Exercise: Draw a triangle: write down 3 things that will make today great
Lesson #3: There is science supporting positivity and gratitude
Coherence=optimal coordination between the heart and the mind ==> heartrate variability is a really beautiful sinus curve in someone who is completely in a coherent state. Being in this mindset is better for your whole body.
Much more information about coherence and Heart Math at the Heart Math Institute Website found here.
Exercise:
1) Heart focused breathing: 5 breaths in/5 breaths out (requires nothing more than the breath)
2) Inner coherence: use positive emotions or feelings of gratitude to establish a coherent beat (using heart math monitor)
And finally, keep a gratitude journal. Even in these hard times, there are big and small things to be grateful for.
Surviving Residency: The Professional Socialization of Family Physicians (Addison 4/20/2022)
Many many thanks to Dr. Ritch Addison for his wonderful Grand Rounds this morning (and his 40+ years of teaching and mentorship at Santa Rosa Family Medicine Residency. It felt like a warm cup of perfectly brewed tea to sit and listen to Ritch share his observations from the professional socialization of family physicians.
For those of you who missed it, the recorded presentation is available HERE and is definitely worth watching!
I have jotted down just a few notes. The talk is definitely best absorbed by listening/watching.
To start, Ritch asked us to consider what resonates with you?
- How do physicians get trained?
- How is residency a process of habit formation?
- How is residency a "stress test" of emotional capacity?
A long time ago (40+ years) in a galaxy (not so) far far away, Dr. Ritch Addison followed nine family medicine interns around for three years-- "I wanted to see what they did." His notebook always in hand, Ritch took call with them, observed them delivering babies, suturing folks in the ER, race to clinic, etc. For three years, he watched them live and process their entire residency training experience.
Today's talk was a summary of observations and models derived from that research. Ritch highlighted a number of important themes:
Surviving residency involves a TON of immediate issues that new R1s are confronted with
- information overload
- work overload
- dying patients
- control
- time pressures
- sleep deprivation
- inexperience
- responsibility
Working relationships are a complex piece of residency identify formation. Relationships with:
- patients
- nurses
- providers
- attendings
- private doctors
- faculty
- other residents
- AND. . . family (which often takes a back seat because residency can be totalizing)
Spheres of existence evolve over time
work education life outside
initial purpose/weight take care of patient learn family medicine maintain some QOL
evolves into GET done do procedures whatever is left
There is an inherent conflict and contradiction between a resident's ideals/goals/visions (expectations) and the everyday practices of being a resident.
Ritch finished off with his assessment of the "modes of surviving"
Over-reflecting: too much self reflection (favorite patient dies, yelled at by attending, make a mistake)
Covering over: using little self-reflection, so focused on what you are doing you cannot see what is happening to you
Moving between these two takes wide movements and is extremely jarring. How do residents learn to move between these modes? Ritch said clearly that it's really NOT about finding the sweet spot of reflection, but rather being able to smooth out the space and integrate these two forms of being.
Finally, Ritch introduced the birth of the Personal and Professional Development groups (P&PD) that really were birthed from the desire of residents to facilitate the movement between these two spaces-- to smooth it out. After all, everybody feels the same way. What happens when we talk about our experiences? We start to resolve the two modes. . .
Ritch ended with an excerpt from The Heroes Walk, by Anita Rau Badami on the physician-patient relationship. Listen to him read it at the end of the recording. That is what family medicine is all about, right? The most meaningful way we can bring health to people.
Why Prescribe Single Pill Combinations? (Toub, 10/14/2026)
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